Related Experiment Video
Updated: Aug 5, 2025

05:41
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
690
Thyroid disease in pregnancy
Yew Wen Yap1, Emeka Onyekwelu2, Uazman Alam3
1Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK yew.yap@liverpoolft.nhs.uk.
Clinical Medicine (London, England)
|March 23, 2023
Summary
Pregnancy involves significant thyroid gland metabolic changes. This review covers thyroid physiology and management of hyperthyroidism, hypothyroidism, and nodules during pregnancy.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Obstetrics
Background:
- Pregnancy induces substantial metabolic alterations impacting thyroid function.
- Understanding these physiological changes is crucial for managing thyroid disorders in pregnant patients.
Approach:
- This review synthesizes current knowledge on thyroid physiology during pregnancy.
- It details the management strategies for common thyroid conditions, including hyperthyroidism, hypothyroidism, and thyroid nodules.
Key Points:
- Maternal thyroid hormone production and metabolism are significantly altered during pregnancy.
- Thyroid dysfunction in pregnancy can affect both maternal and fetal outcomes.
- Management requires careful consideration of safety and efficacy for both mother and fetus.
Conclusions:
- Accurate diagnosis and timely management of thyroid disorders are essential in pregnancy.
- This review provides a comprehensive overview for clinicians managing thyroid conditions in pregnant individuals.
- Further research is warranted to optimize treatment protocols and improve patient outcomes.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
4.8K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.8K
Functions of Thyroid Hormones
2.9K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.9K
The Thyroid Gland
4.1K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.1K
Diabetes Mellitus: Type 2 and Gestational
2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Pathophysiology of Diabetes
1.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.1K
Teratogenicity
2.6K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.6K

