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Cystatin SN in type 2 inflammatory airway diseases

Bing Yan1, Yimin Ren1, Chang Liu1

  • 1Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Nasal Diseases, Beijing Laboratory of Allergic Diseases, Beijing Institute of Otolaryngology, Beijing, China; Key Laboratory of Otolaryngology Head and Neck Surgery (Ministry of Education of China), Beijing Institute of Otolaryngology, Beijing, China; Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China.

The Journal of Allergy and Clinical Immunology
|March 23, 2023
PubMed
Summary

Cystatin SN (CST1) plays a dual role in airway inflammation, protecting tissues physiologically but amplifying Type 2 (T2) immunity pathologically. This review explores its role in T2 inflammatory airway diseases.

Keywords:
Airway diseasescystatin SNtype 2 immunity

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