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Updated: Aug 5, 2025

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
Early Outcomes in Renal Transplantation With Routine Intraoperative Duplex Ultrasound
Linda Thebridge1, Charles Fisher1, Vikram Puttaswamy1
1University of Sydney, Camperdown, Australia; Department of Vascular Surgery, Royal North Shore Hospital, St Leonards, Australia.
Insights
Routine intraoperative ultrasound in renal transplantation identifies vascular issues, reducing early graft loss from surgical factors. This imaging technique offers significant benefits for kidney transplant outcomes.
Area of Science:
- Nephrology
- Surgical Innovation
- Medical Imaging
Background:
- Intra-operative duplex ultrasound scanning is feasible during renal transplantation.
- Its routine clinical value in practice remains unestablished.
Purpose of the Study:
- To evaluate the impact of routine intraoperative ultrasound on early graft loss in renal transplantation.
- To determine if intraoperative ultrasound identifies otherwise unrecognized vascular abnormalities.
Main Methods:
- 331 consecutive adult renal transplants underwent intraoperative scanning.
- Early graft losses were compared to data from the ANZDATA Registry.
Main Results:
- 9 overt vascular abnormalities were corrected pre-scan; 4 venous outflow restrictions and 11 major vascular revisions were identified and addressed.
- 32 grafts were repositioned for improved perfusion; no vascular revisions were needed for these.
- No early graft losses due to surgical or technical reasons occurred, compared to 1.0% in the registry (P=0.077).
Conclusions:
- Routine intraoperative ultrasound is beneficial in renal transplantation.
- It identifies unrecognized vascular abnormalities, reducing early graft losses attributed to surgical factors.
Background:
While intra-operative duplex ultrasound scanning can be readily performed in renal transplantation, the value of this intervention in routine practice is not established.
Methods:
Three hundred thirty-one consecutive single renal transplants in adult recipients underwent intraoperative scanning at implantation. Early graft losses were compared with those recorded in the ANZDATA Registry.
Results:
Nine overt vascular abnormalities were corrected prior to scanning. Four further suspected venous outflow restrictions were confirmed by ultrasound and revised. Another 11 major vascular revisions were performed following intraoperative ultrasound consisting of 7 otherwise unsuspected inflow abnormalities, all corrected, and 4 anastomoses redone to reposition the graft. Thirty-two (9.7%) grafts were repositioned under ultrasound guidance to improve cortical perfusion but without vascular revision. One graft with hyperacute rejection was explanted 4 days postimplantation and one graft with primary nonfunction remained well perfused. Two patients died within 90 days, both with functioning grafts. Twenty-three grafts were re-explored within 7 days, including 9 solely for graft hypoperfusion. There were no postoperative arterial thromboses and, at re-exploration, no arterial anastomoses required revision. There were no postoperative venous thromboses, although one venous anastomosis was revised. No grafts were lost within 90 days for surgical or technical reasons compared with 76 (1.0%) of 7603 contemporaneous grafts in the ANZDATA Registry (P = .077 Fisher's exact test, P = .069 χ2 test).
Conclusions:
The routine use of intraoperative ultrasound appears to be of benefit by identifying otherwise unrecognized vascular abnormalities, leading to a reduction in early graft losses because of surgical factors.
Related Concept Videos
Imaging Studies II: Ultrasonography
Kidney Transplant II: Surgical Procedure
Kidney Transplant III: Nursing Management
Imaging Studies VII: Vascular Imaging
Kidney Transplant I: Introduction
Imaging Studies V: Intravenous Urography and Retrograde Pyelography

