Biogenic metallic nanoparticles as enzyme mimicking agents.
Khanyisile Ngcongco1, Suresh Babu Naidu Krishna2, Karen Pillay1
1School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
Frontiers in Chemistry
|March 24, 2023
Summary
Green synthesis of metallic nanoparticles using biological systems offers a sustainable, eco-friendly, and economical alternative. Research explores nanoparticle characteristics, enzymatic activity, and capping agents to enhance functionality and reduce toxicity for diverse applications.
Area of Science:
- * Biotechnology and Nanomaterials Science
Background:
- * Traditional nanomaterial synthesis methods often involve toxic, polluting, and expensive processes.
- * Biological systems (plants, bacteria, fungi) offer sustainable, eco-friendly, and economical routes for nanomaterial production.
- * Biogenic nanoparticles possess unique physicochemical properties enabling diverse applications in biomedicine, biotechnology, environmental science, and engineering.
Purpose of the Study:
- * To review the intrinsic enzymatic mimetic activity of biogenic metallic nanoparticles.
- * To discuss the cytotoxic effects of nanoparticles and the role of capping agents in mitigating toxicity.
- * To summarize recent advancements in green synthetic strategies for metallic nanoparticles.
Main Methods:
- * Literature review of current research on biosynthesis of metallic nanoparticles.
- * Analysis of physicochemical properties of biogenic nanoparticles.
- * Examination of enzymatic mimetic activity and cytotoxic effects.
- * Evaluation of capping agents as reducing and stabilizing agents.
Main Results:
- * Biogenic metallic nanoparticles exhibit intrinsic enzymatic mimetic activity.
- * Nanoparticle physicochemical properties influence cytotoxicity.
- * Capping agents play a crucial role in reducing toxicity and enhancing nanoparticle stability.
- * Various green synthetic strategies for metallic nanoparticles have been developed.
Conclusions:
- * Biosynthesis offers a sustainable and efficient approach to producing functional metallic nanoparticles.
- * Understanding nanoparticle properties and employing capping agents are key to safe and effective applications.
- * Continued research in green synthesis will drive innovation in nanomaterial development for various scientific fields.


