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Updated: Aug 5, 2025

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
Synthesis and reactivity of azole-based iodazinium salts
Thomas J Kuczmera1, Annalena Dietz1, Andreas Boelke1
1Institute for Organic and Analytical Chemistry, University of Bremen, 28359 Bremen, Germany.
Abstract:
A systematic investigation of imidazo- and pyrazoloiodazinium salts is presented. Besides a robust synthetic protocol that allowed us to synthesize these novel cyclic iodonium salts in their mono- and dicationic forms, we gained in-depth structural information through single-crystal analysis and demonstrated the ring opening of the heterocycle-bridged iodonium species. For an exclusive set of dicationic imidazoiodaziniums, we show highly delicate post-oxidation functionalizations retaining the hypervalent iodine center.
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