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Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

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Related Experiment Video

Updated: Aug 5, 2025

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Characterizing the Bone Marrow Environment in Advanced-Stage Myelofibrosis during Ruxolitinib Treatment Using PET/CT

Stefanie Slot¹, Cristina Lavini², Gerben J C Zwezerijnen³

¹Department of Hematology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

Tomography (Ann Arbor, Mich.)

|March 24, 2023

Summary

Advanced imaging techniques like PET/CT and MRI can visualize myelofibrosis bone marrow abnormalities. Early treatment response in myelofibrosis patients was reflected by T1-weighted MRI, indicating imaging

Area of Science:

Hematology
Radiology
Medical Imaging

Background:

Myelofibrosis diagnosis relies on bone marrow biopsy, which has limitations like sampling errors.

Keywords:

MRI PET/CT diagnostic accuracy myelofibrosis ruxolitinib

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Bone marrow (BM) abnormalities in myelofibrosis are heterogeneous, complicating imaging technique selection.

Exploratory studies suggest imaging may offer an alternative for evaluating myelofibrosis disease activity.