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Nanosilver-functionalized polysaccharides as a platform for wound dressing.

Syam Mohan1,2,3, Pranay Wal4, Kamla Pathak5

  • 1School of Health Sciences, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India.

Environmental Science and Pollution Research International
|March 24, 2023
PubMed
Summary

Naturally sourced polysaccharides and nanosilver offer affordable, biocompatible wound dressings. This review details nanosilver-polysaccharide wound dressings for chronic wound healing, covering preparation, performance, and future research.

Keywords:
ChitosanDextranHyaluronanPolysaccharideSilver nanoparticlesWound dressings

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Wound Healing

Background:

  • Naturally sourced polysaccharides are promising for wound dressings due to availability, cost, and biocompatibility.
  • Nanosilver (AgNPs) exhibits broad-spectrum antimicrobial activity and low drug resistance, making it valuable for wound treatment.
  • Combining polysaccharides with nanosilver creates effective wound dressings for chronic wound management.

Purpose of the Study:

  • To review the preparation methods, classification, and antibacterial performance of nanosilver-based polysaccharide wound dressings.
  • To summarize recent advancements in silver nanotechnology for wound care applications.
  • To provide guidance for future research in nanosilver-functionalized polysaccharide wound dressings.

Main Methods:

  • Literature review of scientific publications on nanosilver-polysaccharide wound dressings.
  • Analysis of preparation techniques and characterization of nanosilver-polysaccharide composites.
  • Evaluation of antibacterial efficacy and biocompatibility data from existing studies.

Main Results:

  • Various methods exist for preparing nanosilver-polysaccharide wound dressings.
  • These dressings demonstrate significant antibacterial activity against a wide range of pathogens.
  • The combination enhances wound healing properties compared to individual components.

Conclusions:

  • Nanosilver-functionalized polysaccharide wound dressings are a cost-effective and efficient option for chronic wound healing.
  • Further research into advanced preparation and application methods is warranted.
  • This field holds significant potential for improving patient outcomes in wound care.