Related Experiment Video
Updated: Aug 5, 2025

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
Published on: June 30, 2023
Measuring misclassification of Covid-19 as garbage codes: Results of investigating 1,365 deaths and implications for
Elisabeth B França1,2, Lenice H Ishitani2, Daisy Maria Xavier de Abreu2
1Graduate Program in Public Health, School of Medicine, Federal University of Minas Gerais - Belo Horizonte, Minas Gerais, Brazil.
Insights
Brazil
Area of Science:
- Epidemiology
- Public Health
- Vital Statistics
Background:
- Misclassification of Coronavirus Disease-2019 (COVID-19) mortality is a significant issue in Brazil.
- Deaths attributed to garbage codes (GC) obscure the true COVID-19 death toll.
- Accurate vital statistics are crucial for understanding the pandemic's impact.
Purpose of the Study:
- To quantify COVID-19 mortality misclassification in Brazilian hospitals.
- To identify factors contributing to misclassification.
- To assess the implications for national vital statistics.
Main Methods:
- Analysis of hospital deaths assigned to garbage codes in three Brazilian state capitals.
- Review of medical charts and forensic reports by physicians.
- Re-assignment of underlying causes based on standardized criteria.
- Extrapolation of findings to national data.
Main Results:
- COVID-19 was confirmed in 17.3% of investigated GC deaths (0-59 years) and 25.5% (≥60 years).
- Garbage codes accounted for 211,611 registered deaths in 2020.
- National extrapolation suggests an undercount of at least 18% in 2020 COVID-19 deaths.
Conclusions:
- Significant undercounting of COVID-19 deaths occurred in Brazil due to misclassification.
- The true burden of COVID-19 in Brazil's 2020 vital statistics was likely underestimated.
- Addressing garbage code deaths is essential for accurate pandemic surveillance.
Abstract:
The purpose of this article is to quantify the amount of misclassification of the Coronavirus Disease-2019 (COVID-19) mortality occurring in hospitals and other health facilities in selected cities in Brazil, discuss potential factors contributing to this misclassification, and consider the implications for vital statistics. Hospital deaths assigned to causes classified as garbage code (GC) COVID-related cases (severe acute respiratory syndrome, pneumonia unspecified, sepsis, respiratory failure and ill-defined causes) were selected in three Brazilian state capitals. Data from medical charts and forensic reports were extracted from standard forms and analyzed by study physicians who re-assigned the underlying cause based on standardized criteria. Descriptive statistical analysis was performed and the potential impact in vital statistics in the country was also evaluated. Among 1,365 investigated deaths due to GC-COVID-related causes, COVID-19 was detected in 17.3% in the age group 0-59 years and 25.5% deaths in 60 years and over. These GCs rose substantially in 2020 in the country and were responsible for 211,611 registered deaths. Applying observed proportions by age, location and specific GC-COVID-related cause to national data, there would be an increase of 37,163 cases in the total of COVID-19 deaths, higher in the elderly. In conclusion, important undercount of deaths from COVID-19 among GC-COVID-related causes was detected in three selected capitals of Brazil. After extrapolating the study results for national GC-COVID-related deaths we infer that the burden of COVID-19 disease in Brazil in official vital statistics was probably under estimated by at least 18% in the country in 2020.
Related Concept Videos
Principles of Disease Surveillance
Bias in Epidemiological Studies
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
Censoring Survival Data
Statistical Methods for Analyzing Epidemiological Data
Causality in Epidemiology

