Related Experiment Video
Updated: Aug 5, 2025

05:35
Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
324
Can the Sandwich Method Be an Alternative Treatment Choice for BPH Patients With Large Prostates?
Tsu-Chen Lin1, Chen-Pang Hou2, Yu-Chao Hsu3
1Division of Urology, Department of Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Urology
|March 24, 2023
Summary
The sandwich method, combining GreenLight photoselective vaporization and bipolar transurethral resection, is as effective and safe as enucleation for treating large prostates in benign prostatic hyperplasia (BPH) patients.
Area of Science:
- Urology
- Surgical Techniques
- Benign Prostatic Hyperplasia (BPH) Management
Background:
- Benign prostatic hyperplasia (BPH) affects a significant number of aging men.
- Surgical intervention is often required for symptomatic BPH.
- Large prostate volumes (≥ 80 g) present unique surgical challenges.
Purpose of the Study:
- To compare the efficacy and safety of the sandwich method (GreenLight photoselective vaporization [GLPVP] + bipolar transurethral resection [B-TURP]) with the enucleation method for BPH patients with large prostates (≥ 80 g).
Main Methods:
- Retrospective analysis of 96 BPH patients (55 sandwich group, 41 enucleation group) between 2014-2021.
- Primary outcome: comparison of uroflowmetry results.
- Secondary outcome: comparison of complication rates and perioperative parameters.
Main Results:
- Comparable uroflowmetry results between groups, with a higher postoperative flow rate in the enucleation group.
- Sandwich method had longer operating time; enucleation group had more Foley irrigations.
- Similar postoperative complication rates observed in both surgical approaches.
Conclusions:
- The sandwich method demonstrates comparable efficacy and safety to enucleation for BPH with prostate volume ≥ 80 g.
- This technique offers a viable alternative surgical option for surgeons proficient in GLPVP and B-TURP for managing large prostates.
Related Concept Videos
Disorders of the Male Reproductive System
491
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
491
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
207
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
207

