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Published on: February 14, 2017
Diagnostic accuracy of heart auscultation for detecting valve disease: a systematic review
Anne Herefoss Davidsen1, Stian Andersen2, Peder Andreas Halvorsen2
1General Practice Research Unit, Department of Community Medicine, UiT The Arctic University, Tromso, Norway anne.h.davidsen@uit.no.
Insights
Heart auscultation
Area of Science:
- Cardiology
- Diagnostic Accuracy
- Internal Medicine
Background:
- Valvular heart disease (VHD) diagnosis often relies on auscultation.
- The diagnostic accuracy of auscultation for VHD needs clarification.
Approach:
- A systematic literature search identified 23 diagnostic studies comparing heart auscultation to echocardiography or angiography.
- Studies published between 1967 and 2021 were included.
- Risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool.
Key Points:
- Sensitivity for auscultation ranged from 30% to 100%, specificity from 28% to 100%, and likelihood ratios (LRs) from 1.35 to 26.
- Data from general practice is sparse.
- Most studies utilized cardiologists or internal medicine specialists.
Conclusions:
- Diagnostic accuracy of auscultation for VHD varies significantly.
- Medical doctors should not solely rely on auscultation for VHD detection.
- Further research is required to integrate auscultation with other clinical findings for improved VHD diagnosis.
Objective:
The objective of this study was to determine the diagnostic accuracy in detecting valvular heart disease (VHD) by heart auscultation, performed by medical doctors.
Design/Methods:
A systematic literature search for diagnostic studies comparing heart auscultation to echocardiography or angiography, to evaluate VHD in adults, was performed in MEDLINE (1947-November 2021) and EMBASE (1947-November 2021). Two reviewers screened all references by title and abstract, to select studies to be included. Disagreements were resolved by consensus meetings. Reference lists of included studies were also screened. The results are presented as a narrative synthesis, and risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies-2.
Main Outcome Measures:
Sensitivity, specificity and likelihood ratios (LRs).
Results:
We found 23 articles meeting the inclusion criteria. Auscultation was compared with full echocardiography in 15 of the articles; pulsed Doppler was used as reference standard in 2 articles, while aortography and ventriculography was used in 5 articles. One article used point-of-care ultrasound. The articles were published from year 1967 to 2021. Sensitivity of auscultation ranged from 30% to 100%, and specificity ranged from 28% to 100%. LRs ranged from 1.35 to 26. Most of the included studies used cardiologists or internal medicine residents or specialists as auscultators, whereas two used general practitioners and two studied several different auscultators.
Conclusion:
Sensitivity, specificity and LRs of auscultation varied considerably across the different studies. There is a sparsity of data from general practice, where auscultation of the heart is usually one of the main methods for detecting VHD. Based on this review, the diagnostic utility of auscultation is unclear and medical doctors should not rely too much on auscultation alone. More research is needed on how auscultation, together with other clinical findings and history, can be used to distinguish patients with VHD.
Prospero Registration Number:
CRD42018091675.
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