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Updated: Aug 5, 2025

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
Published on: March 15, 2024
Functional recovery with peripheral nerve block versus general anesthesia for upper limb surgery: a systematic review
Jennifer Héroux1, Pierre-Olivier Bessette2, Emilie Belley-Côté3,4
1Department of Anesthesiology, Université de Sherbrooke, Sherbrooke, QC, Canada. jennifer.heroux@usherbrooke.ca.
Peripheral nerve block (PNB) for upper limb surgery did not show significant superiority over general anesthesia for functional recovery. More research is needed to determine long-term benefits and guide clinical practice.
Area of Science:
- Anesthesiology
- Orthopedic Surgery
- Evidence-Based Medicine
Background:
- Peripheral nerve block (PNB) is a common anesthetic technique for orthopedic upper limb surgery.
- PNB inhibits nerve signal transmission, potentially improving functional recovery compared to general anesthesia.
- This review assesses PNB's impact on postoperative functional recovery in orthopedic upper limb surgery.
Conclusions:
- Current evidence is limited, failing to demonstrate a clear benefit of PNB on functional recovery after orthopedic upper limb surgery.
- Further research, including long-term studies, is necessary to fully understand PNB's impact.
- A prospective study is underway to further investigate functional recovery outcomes.
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