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Related Experiment Video

Updated: Aug 5, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
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The relationship between depression and cognitive performance in multiple sclerosis: A meta-analysis.

Manuela Altieri1,2, Francesco Cerciello1, Antonio Gallo2

  • 1Department of Psychology, University of Campania "Luigi Vanvitelli", Caserta, CE, Italy.

The Clinical Neuropsychologist
|March 25, 2023
PubMed
Summary
This summary is machine-generated.

This meta-analysis found that depression in multiple sclerosis (MS) patients is linked to cognitive impairments, particularly in attention and processing speed. These findings highlight the importance of addressing depressive symptoms to improve cognitive function in individuals with MS.

Keywords:
Multiple sclerosiscognitioncognitive performancedepressionmeta-analysis

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • The relationship between depression and cognitive function in multiple sclerosis (MS) patients remains unclear, with inconsistent findings regarding specific cognitive domains affected.
  • Depressive symptomatology is a common comorbidity in MS, potentially impacting quality of life and disease management.

Conclusions:

  • Higher levels of depressive symptomatology in MS patients are associated with more pronounced difficulties in various cognitive functions.
  • Cognitive impairments, particularly in attention and information processing, are significantly linked to depression in individuals with MS.
  • These findings underscore the need to consider and manage depressive symptoms to potentially mitigate cognitive deficits in the multiple sclerosis population.