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Viral- and tumor-reactive natural killer cells

Jianhua Yu1, Michael A Caligiuri2

  • 1Department of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, CA 91010, USA; Hematologic Malignancies Research Institute, City of Hope National Medical Center, Los Angeles, CA 91010, USA; Department of Immuno-Oncology, City of Hope, Los Angeles, CA 91010, USA; City of Hope Comprehensive Cancer Center, Los Angeles, CA 91010, USA.

Seminars in Immunology
|March 25, 2023
PubMed
Summary

Natural killer (NK) cells have new roles in immunity. Understanding their recognition and response mechanisms, like Fc-bridged cellular cytotoxicity (FcBCC) and myeloid leukemia interactions, improves disease treatment.

Keywords:
FcBCCHerpes virusIL-15NK cellsNatural killerTRACK-NK cellsTumor cellsTumor- reactiveViral-reactive

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