Persistent foramen of Huschke: Clinical manifestations and complications, systematic review

Louis Chappuis1, Isabelle Barthelemy2, Nathalie Pham Dang2

  • 1Oral and Maxillofacial Department, Estaing Hospital, CHU Clermont-Ferrand, F-63003, Clermont-Ferrand, France; Université d'Auvergne, Faculty of Medicine, F- 63001, Clermont-Ferrand cedex 1, France.

Insights

Persistent foramen of Huschke, an anatomical variation, can cause ear infections and tinnitus. Early recognition and treatment are crucial to prevent temporomandibular joint (TMJ) destruction and chronic pain.

Area of Science:

  • Anatomy
  • Otolaryngology
  • Dentistry

Background:

  • The foramen of Huschke is a bone defect with diverse clinical presentations that can lead to severe complications.
  • Clinical history and imaging findings are often non-specific, highlighting the need for accurate diagnosis and management of pathologies associated with this persistent foramen.

Purpose of the Study:

  • To review and summarize the clinical manifestations and complications of a persistent foramen of Huschke in adult patients.
  • To consolidate findings from reported literature cases and provide insights into this anatomical variation.

Main Methods:

  • A comprehensive literature search was performed across PubMed, Cochrane Library, ScienceDirect, and Embase databases up to November 2022.
  • Key search terms included "foramen of Huschke" and "foramen tympanicum" to identify relevant studies and case reports.

Main Results:

  • Out of 74 initially identified papers, 21 were selected, encompassing 46 patients and one additional case.
  • The most frequently reported symptoms were otitis (63%), otorrhea (28.26%), and masticatory tinnitus (19.57%).
  • Computed tomography (CT) scans were the primary diagnostic tool (95.65%), and surgical intervention was the most common treatment (28.26%).

Conclusions:

  • A persistent foramen of Huschke should be suspected in patients presenting with otitis, otorrhea, and masticatory tinnitus.
  • Understanding this anatomical variation is vital for managing temporomandibular joint (TMJ) disorders and preventing conditions like TMJ septic arthritis.
Abstract