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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
[Macrolide-resistant Mycoplasma pneumoniae: Do we know the situation in Europe?]
A I Álvaro Varela1, A Aguinaga Pérez, A Navascués Ortega
1Ana Isabel Álvaro Varela, Servicio de Microbiología Clínica, Hospital Universitario de Navarra, Pamplona, Spain. ai.alvaro.varela@navarra.es.
Abstract:
Mycoplasma pneumoniae is a bacterium that lacks a cell wall. It produces infections all It produces infections world-wide, in epidemic outbreaks every 4-7 years, or endemically. Its clinical manifestations occur mostly in the respiratory tract and it is a common cause of atypical pneumonia. The treatment is with macrolides, tetracyclines or fluoroquinolones. Since 2000, an increase in resistance to macrolides has been detected worldwide, being more frequent in Asia. In Europe the frequency of resistance ranges between 1% and 25%, depending on the country. Molecular techniques and serology techniques provides very high sensitivity in diagnostic confirmation, being very useful for detecting and controlling M. pneumoniae outbreaks. The detection of resistance to macrolides requires a sequencing technique.
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