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The effect of node features on GCN-based brain network classification: an empirical study.

Guangyu Wang1, Limei Zhang1,2, Lishan Qiao1,2

  • 1Liaocheng University, Liaocheng, China.

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|March 27, 2023
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Summary
This summary is machine-generated.

This study explores how different node features impact graph convolutional network (GCN) performance for classifying brain functional networks (BFNs). Node correlation features generally yield higher accuracy in brain disorder identification.

Keywords:
Autism spectrum disorderEmpirical studyGraph convolutional networkMild cognitive impairmentNode features

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Area of Science:

  • Neuroscience
  • Machine Learning
  • Medical Informatics

Background:

  • Brain functional network (BFN) analysis is crucial for identifying neurological and mental diseases.
  • Graph convolutional networks (GCNs) are suitable for BFN classification due to their graph structure.
  • GCNs require node features, but their impact on BFN classification is understudied.

Purpose of the Study:

  • To systematically investigate the influence of various node feature types on GCN-based brain disorder classification.
  • To compare the performance of different node feature strategies for GCNs applied to BFNs.

Main Methods:

  • Empirical study of five node feature types: original fMRI signals, one-hot encoding, node statistics, node correlation, and combinations.
  • Utilized GCNs for classification on two benchmark brain disorder databases.
  • Evaluated classification performance based on different node feature inputs.

Main Results:

  • Node feature selection significantly impacts GCN performance in brain disorder classification.
  • Node correlation features generally outperform original fMRI signals and manually extracted statistical features.
  • Combined node features may offer further improvements, warranting further investigation.

Conclusions:

  • The choice of node features is critical for optimizing GCNs in BFN analysis for disease identification.
  • Node correlation emerges as a highly effective feature for GCN-based brain disorder classification.
  • Future research should explore advanced feature engineering and combinations for enhanced diagnostic accuracy.