Race-related population attributable fraction of preventable risk factors of dementia: A Latino population-based
Wyllians Vendramini Borelli1,2, Carolina Rodrigues Formoso2,3, Andrei Bieger3,4
1Pharmacology and Therapeutics Research Program Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil.
Background:
Risk factors for dementia have distinct frequency and impact in relation to race. Our aim was to identify differences in modifiable risk factors of dementia related to races and estimate their population attributable fraction (PAF).
Methods:
An epidemiological cohort was used to estimate the prevalence of 10 modifiable risk factors for dementia among five races-White, Black, Brown, Asian, and Indigenous. Sample weighting was used to estimate the prevalence and PAF of each risk factor in each race.
Results:
A total of 9070 individuals were included. Overall adjusted PAF was the lowest in Indigenous (38.9%), and Asian individuals (41.2%). Race-related prevalence of individual risk factors was widely variable in our population, but hearing loss was the most important contributor to the overall PAF in all races.
Conclusions:
Public policies aiming to reduce preventable risk factors for dementia should take into consideration the race of the target populations.
Highlights:
Preventable risk factors for dementia vary according to race.Hearing loss presented the highest prevalence among all races studied.Indigenous and Asian individuals presented the lowest population attributable fractions.Black and Brown individuals were more vulnerable to social determinants.
More Related Videos
Related Concept Videos
Dementia
The progression of dementia is generally gradual....
Stereotypes, Prejudice, and Discrimination
Bias in Epidemiological Studies
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
Confounding in Epidemiological Studies


