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Updated: Aug 5, 2025

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
Low-vision intervention for oculocutaneous albinism in a Tertiary Eye Care Hospital in India
Sarika Gopalakrishnan1,2, Kalpa Negiloni3, R Vivek Suganthan3
1School of Chemical and Biotechnology, Shanmugha Arts, Science, Technology and Research Academy University, Thanjavur, Tamil Nadu, India.
Purpose:
The objective of this study on patients with albinism in different age groups was to compare their level of visual impairment with the low-vision intervention (LVI) and its benefit.
Methods:
The medical records of 72 patients with low vision secondary to albinism who were referred to the low vision care clinic from 2015 to 2017 were analyzed. This included the demographic profile such as age, gender, occupation, ocular history, visual acuity status, and type of low-vision device (LVD) preferred. The LVDs prescribed and its subsequent improvement was compared.
Results:
In this data, 70 (97.2%) people had oculocutaneous albinism and 2 (2.8%) had ocular albinism. Majority of the patients had hyperopic astigmatism 42 (58.3%) and with-the-rule astigmatism 58 (93.5%). Presenting mean visual acuity for distance was noted to be 0.88 logMAR which improved to 0.83 logMAR with the help of spectacle correction. The most commonly prescribed LVD was a dome magnifier for 15 (34.9%) patients. In all the patients, there was statistically significant improvement (P < 0.05) in near vision with the help of LVDs.
Conclusion:
The study highlights the importance of appropriate LVI for each subdivided age group. Patients with albinism who have received medical and surgical treatment have no or a limited role in restoring useful vision.
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