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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Related Experiment Video

Updated: Aug 5, 2025

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
07:40

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

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Cutaneous T-cell lymphoma developing in surgical scars post cardiac surgery: A case study.

Sarah J Touyz1, Feras M Ghazawi2, Elena Netchiporouk3

  • 1Department of Acute Internal Medicine, Salford Royal NHS Foundation Trust, Salford, UK.

SAGE Open Medical Case Reports
|March 27, 2023
PubMed
Summary

Primary cutaneous T-cell lymphoma can develop in surgical scars months after surgery. This rare non-Hodgkin lymphoma presentation was successfully treated with radiotherapy.

Keywords:
Cutaneous T-cell lymphomapost-operativepost-surgicalscarsurgery

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Cutaneous T-cell lymphomas (CTCL) are malignant skin lymphomas with unclear pathogenesis.
  • Persistent antigen stimulation and inflammatory microenvironments are implicated in CTCL development.

Observation:

  • A case of primary CTCL arose in two surgical scars 6 months post-operation.
  • The lesions were localized to the sites of prior surgical trauma.

Findings:

  • The CTCL presented as localized disease in surgical scars.
  • Successful treatment was achieved with external beam radiotherapy.

Implications:

  • This case suggests CTCL can arise in surgical scars relatively quickly after trauma.
  • It highlights the importance of considering CTCL in skin lesions developing at injury sites.
  • This contributes to understanding CTCL development following surgery or foreign body presence.