Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

13.7K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epidemiological characteristics of amebiasis in Japan from 2001 to 2022.

PloS one·2026
Same author

An algorithm to calculate physical density of biomedical objects having 3 ≤ Z<sub>eff</sub> ≤ 20: an application study using clinical photon-counting computed tomography equipment.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2026
Same author

The Missing Step in Fall Prevention: Why Recommendations Fail in Practice.

Journal of general internal medicine·2026
Same author

Online Search Trends on Child Abuse During the COVID-19 Pandemic Using the Most Widely Used Search Engine: Retrospective Observational Study.

JMIR pediatrics and parenting·2026
Same author

CD4/CD8 ratio is associated with structural reorganization of vaccine-induced immune responses in people living with HIV.

Frontiers in immunology·2026
Same author

Distribution of influenza A virus receptors in tissues of South American marine wildlife.

Veterinary research communications·2026

Related Experiment Video

Updated: Aug 5, 2025

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

253

Clinical prediction rule for bacterial arthritis: Chi-squared automatic interaction detector decision tree analysis

Seiko Kushiro1, Sayato Fukui1, Akihiro Inui1

  • 1Department of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.

SAGE Open Medicine
|March 27, 2023
PubMed
Summary

Identifying bacterial arthritis early is crucial. High-risk patients with elevated C-reactive protein or specific platelet counts can be identified for prompt treatment.

Keywords:
Bacterial arthritischi-squared automatic interaction detector analysispredictive rulerisk factors

More Related Videos

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

11.2K
Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

336

Related Experiment Videos

Last Updated: Aug 5, 2025

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

253
Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

11.2K
Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

336

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Bacterial arthritis diagnosis often relies on synovial testing, which can be invasive.
  • Predictors for bacterial arthritis beyond synovial fluid analysis are not well-defined.
  • Early identification of bacterial arthritis is critical for effective treatment and patient outcomes.

Purpose of the Study:

  • To identify demographic, symptomatic, and laboratory predictors of bacterial arthritis.
  • To develop a risk stratification model for bacterial arthritis excluding synovial testing.
  • To enable earlier initiation of treatment for bacterial arthritis.

Main Methods:

  • Retrospective cross-sectional study at a university hospital (2010-2020).
  • Analysis of clinical data from 460 patients undergoing arthrocentesis.
  • Chi-squared automatic interaction detector (CHAID) decision tree analysis to identify risk factors.

Main Results:

  • 14.8% of patients (68/460) had bacterial arthritis.
  • High C-reactive protein (>21.09 mg/dL) was associated with a 48.7% incidence of septic arthritis.
  • Specific platelet count ranges (27.70-30.70 × 10⁴/μL) combined with lower C-reactive protein indicated a 36.1% incidence.

Conclusions:

  • The study identified key laboratory markers (CRP and platelet count) for predicting bacterial arthritis risk.
  • A risk stratification model can aid in early identification of high-risk patients.
  • Prompt treatment initiation for high-risk individuals is emphasized.