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Updated: Aug 5, 2025

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
Recent trends in chronic pain medicine
Naveen Malhotra1, Muralidhar Joshi2, Samarjit Dey3
1Department of Cardiac Anaesthesia and Pain Management Centre, Pt. B. D. Sharma PGIMS Rohtak, Haryana, India.
Chronic pain management faces challenges due to complex pathways and varied patient responses. Novel strategies like radiofrequency, regenerative medicine, and neuromodulation offer promising alternatives to traditional treatments.
Area of Science:
- Pain Medicine
- Regenerative Medicine
- Interventional Pain Management
Background:
- Chronic pain is a complex condition with diverse biochemical and biological pathways.
- Individual pain perception varies significantly, complicating treatment.
- Conservative and opioid-based treatments often have inadequate efficacy or undesirable side effects.
Purpose of the Study:
- To review emerging and promising therapeutic modalities for chronic pain management.
- To highlight advanced techniques addressing limitations of current treatments.
Main Methods:
- Review of current literature on novel pain management strategies.
- Identification and categorization of emerging interventional and regenerative techniques.
Main Results:
- Radiofrequency ablation, regenerative biomaterials, platelet-rich plasma, and mesenchymal stem cells show potential.
- Reactive oxygen species scavenger nanomaterials offer a novel approach.
- Ultrasound-guided procedures, endoscopic spinal surgery, vertebral augmentation, and neuromodulation are advancing treatment options.
Conclusions:
- New therapeutic modalities are evolving for safer and more effective chronic pain management.
- These advanced techniques represent a promising future for pain physicians.
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