Cavernous Sinus Thrombosis Linked to COVID-19 Infection: a Case Report

Area of Science:

• Neurology
• Infectious Diseases
• Vascular Medicine

Background:

• COVID-19 (SARS-CoV-2) infection, primarily known for respiratory issues, can manifest with diverse thromboembolic and neurological complications.
• Neurological symptoms in COVID-19 are increasingly recognized, with potential neurotropism affecting the central nervous system and cranial nerves.

Observation:

• A 73-year-old male presented with sudden diplopia and ptosis three days post-COVID-19 diagnosis.
• Initial head CT was unremarkable; however, cerebral MRI revealed right cavernous sinus thrombosis.
• The patient had no prior history of thrombosis.

Findings:

• Cerebral MRI confirmed cavernous sinus thrombosis, a rare complication associated with COVID-19.
• Follow-up imaging demonstrated complete resolution of the thrombosis and recanalization of the cavernous sinus.
• Clinical symptoms of diplopia and fever resolved concurrently with radiological improvement.

Implications:

• This case underscores the potential for COVID-19 to trigger rare vascular events such as cavernous sinus thrombosis.
• Highlights the importance of considering neurological complications in COVID-19 patients, even without typical risk factors.
• Suggests that prompt diagnosis and management can lead to favorable outcomes in these rare cases.