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Related Experiment Video

Updated: Aug 5, 2025

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Prolonged opioid use after distal radius fracture.

Fabian Larrosa Pardo1,2,3, Elisabeth Bondesson1,4, Ingemar F Petersson2

  • 1Faculty of Medicine, Division of Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.

European Journal of Pain (London, England)
|March 27, 2023
PubMed
Summary

Distal radius fractures can lead to prolonged opioid use, particularly in patients with prior opioid or mental health issues. Early rehabilitation and considering past opioid use are key to prevention.

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Area of Science:

  • Orthopedics
  • Pain Management
  • Pharmacology

Background:

  • Distal radius fractures are common injuries.
  • Prolonged opioid use (over 90 days) post-injury increases adverse event risk.
  • Understanding opioid prescription patterns after fracture is crucial.

Purpose of the Study:

  • Investigate opioid prescription patterns following distal radius fractures.
  • Identify pre- and post-fracture factors influencing prolonged opioid use.

Main Methods:

  • Register-based cohort study in Skåne, Sweden (2015-2018).
  • Followed 9369 adult patients for 1 year post-fracture.
  • Analyzed opioid purchases and risk factors using modified Poisson regression.

Main Results:

  • 7.1% of patients experienced prolonged opioid use (4-6 months).
  • Previous opioid use (even discontinued up to 5 years prior) significantly increased risk.
  • Mental illness and surgery also elevated risk; occupational/physical therapy reduced it.

Conclusions:

  • History of mental illness and prior opioid use are key predictors of prolonged use.
  • Rehabilitation and careful consideration of past opioid use are vital for prevention.