Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.8K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.8K
The Thyroid Gland01:23

The Thyroid Gland

4.1K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.1K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.9K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.9K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

379
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
379
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

97
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
97
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

265
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
265

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effectiveness of levothyroxine starting doses after thyroidectomy is compromised by early body variations occurring after surgery.

Endocrine·2026
Same author

The role of nutrition on thyroid health and disease: myths and facts.

Journal of endocrinological investigation·2026
Same author

The pyrazolo[3,4-d]pyrimidine derivative CLM24 has an antineoplastic effect in aggressive dedifferentiated thyroid cancer in vitro.

Endocrine·2026
Same author

Letter to the editor from Virili et al: "Fasting vs non-fasting, dose-adjusted levothyroxine ingestion in hypothyroidism: a randomized clinical trial".

The Journal of clinical endocrinology and metabolism·2026
Same author

Different clinical autoimmune polyglandular syndrome phenotypes among patients with thyroid diseases.

Journal of endocrinological investigation·2026
Same author

Acetate Metabolism in Thyroid Cancer Progression.

International journal of molecular sciences·2026

Related Experiment Video

Updated: Aug 5, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.6K

Microbiota and Thyroid Disease: An Updated Systematic Review.

Ilaria Stramazzo1,2, Silvia Capriello1, Simone Filardo3

  • 1Department of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy.

Advances in Experimental Medicine and Biology
|March 27, 2023
PubMed
Summary

The gut microbiota influences thyroid health, impacting both autoimmune and non-autoimmune thyroid disorders. This gut-thyroid axis highlights a crucial bidirectional relationship for maintaining thyroid homeostasis.

Keywords:
Differentiated thyroid cancerGraves’ diseaseHashimoto’s thyroiditisHypothyroidismMicrobiota

More Related Videos

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.9K
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

1.7K

Related Experiment Videos

Last Updated: Aug 5, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.6K
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.9K
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

1.7K

Area of Science:

  • Endocrinology and Microbiology
  • Investigates the intricate connection between gut microbial communities and thyroid function.

Background:

  • Growing evidence links gut microbiota to thyroid pathology, including autoimmune conditions.
  • Research is expanding to include diverse patient groups and biological niches.

Approach:

  • Systematic review of recent advancements in gut microbiota and thyroid disorder research.
  • Analysis includes metabolomic insights and therapeutic interventions like probiotics.

Key Points:

  • Gut microbiota composition is associated with various thyroid disorders.
  • The relationship extends beyond autoimmunity to non-autoimmune conditions.
  • Microbiota in different niches (saliva, tumor microenvironment) are also studied.

Conclusions:

  • A bidirectional relationship exists between the gut microbiota and thyroid homeostasis.
  • This supports the concept of a "gut-thyroid axis."
  • Further research can inform therapeutic strategies targeting gut microbiota for thyroid health.