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Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia

Sanne S Mooldijk1, Silvan Licher1, Frank J Wolters1

  • 1Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.

JAMA Internal Medicine
|March 27, 2023
PubMed
Abstract

No abstract available in PubMed .

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
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The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
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