Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Imaging in Juvenile Idiopathic Arthritis: A Comprehensive Review.

The Indian journal of radiology & imaging·2026
Same author

Melorheostosis Incidentally Detected during Staging of Colon Carcinoma.

Radiology. Imaging cancer·2026
Same author

Morel Lavallée Lesion Following Excessive Physiotherapy for Ankle Arthritis in a Child with Juvenile Idiopathic Arthritis: Authors' Reply.

Indian journal of pediatrics·2026
Same author

Overcalling an Inflamed Appendix - How Much is Too Much?

Indian journal of pediatrics·2026
Same author

Shaping the landscape of interstitial lung disease in idiopathic inflammatory myopathies: state of the art, evidence gaps and a need for clinical trials.

Clinical and experimental rheumatology·2026
Same author

Morel Lavallée Lesion Following Excessive Physiotherapy for Ankle Arthritis in a Child with Juvenile Idiopathic Arthritis.

Indian journal of pediatrics·2026
Same journal

Erratum for: Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model.

Radiology·2026
Same journal

Erratum for: Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort.

Radiology·2026
Same journal

Erratum for: Blue Rubber Bleb Nevus Syndrome.

Radiology·2026
Same journal

Redefining the Clinical Role of MRI in Endometrial Cancer Staging.

Radiology·2026
Same journal

To Ablate or Not to Ablate: The Colorectal Liver Metastasis Question.

Radiology·2026
Same journal

The Limits of Radiologic Categorization in Pulmonary Nonsolid Nodules.

Radiology·2026
See all related articles

Related Experiment Video

Updated: Aug 5, 2025

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

7.3K

Case 316.

Amit Gupta1, Narendra Bagri1, Stuti Chandola1

  • 1From the Department of Radiodiagnosis and Interventional Radiology (A.G., S.C., M.J.) and Department of Pediatrics (N.B.), All India Institute of Medical Sciences, New Delhi 110029, India.

Radiology
|March 27, 2023
PubMed
Summary
This summary is machine-generated.

A 10-year-old boy with hand joint swelling and short stature was initially misdiagnosed with juvenile idiopathic arthritis. Further investigation revealed a rare genetic disorder affecting bone and joint development.

More Related Videos

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
06:40

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice

Published on: February 10, 2023

1.6K
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
06:16

Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues

Published on: April 26, 2024

781

Related Experiment Videos

Last Updated: Aug 5, 2025

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
10:03

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

7.3K
Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
06:40

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice

Published on: February 10, 2023

1.6K
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
06:16

Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues

Published on: April 26, 2024

781

Area of Science:

  • Pediatric Rheumatology
  • Medical Genetics

Background:

  • A 10-year-old boy presented with a 3-year history of bilateral hand joint swelling and flexion deformities.
  • Symptoms included restricted joint movement without tenderness or morning stiffness, and short stature.
  • Previous treatment for suspected juvenile idiopathic arthritis was ineffective.

Purpose of the Study:

  • To investigate the underlying cause of persistent hand joint swelling and short stature in a pediatric patient.
  • To differentiate from common autoimmune arthropathies like juvenile idiopathic arthritis.

Main Methods:

  • Clinical examination focusing on joint morphology and growth parameters.
  • Laboratory investigations including inflammatory markers (ESR, CRP) and rheumatoid factor.
  • Radiographic skeletal survey to assess bone and joint abnormalities.

Main Results:

  • The patient exhibited non-tender swelling and flexion deformities of metacarpophalangeal and interphalangeal joints.
  • Inflammatory markers and rheumatoid factor were negative, ruling out typical inflammatory arthritis.
  • Short stature (below the third centile) was a significant finding.

Conclusions:

  • The clinical presentation and negative inflammatory markers suggest a diagnosis beyond juvenile idiopathic arthritis.
  • A skeletal survey is crucial for identifying underlying genetic or developmental bone disorders.
  • Further genetic testing is warranted to confirm the diagnosis.