Related Experiment Video
Updated: Aug 5, 2025
02:55
Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
Published on: October 6, 2023
1.5K
Brown Adipose Tissue: Activation and Metabolism in Humans
Imane Hachemi1, Mueez U-Din1,2
1Turku PET Center, Turku University Hospital, Turku, Finland.
Endocrinology and Metabolism (Seoul, Korea)
|March 27, 2023
Summary
Brown adipose tissue (BAT) aids non-shivering thermogenesis and energy expenditure. This review explores how dietary interventions and nutritional agents can activate BAT for weight management by promoting BAT-WAT transdifferentiation.
Area of Science:
- Metabolism and Endocrinology
- Adipose Tissue Biology
- Nutritional Science
Background:
- Brown adipose tissue (BAT) is a key thermogenic organ, primarily activated by cold.
- Emerging research indicates BAT activity extends to thermoneutral and postprandial states.
- BAT exhibits greater energy dissipation than white adipose tissue (WAT) and muscle.
Conclusions:
- Nutrition is central to obesity and weight management strategies.
- Targeting BAT through diet may increase whole-body energy expenditure.
- Further research into nutritional modulation of BAT is warranted for therapeutic applications.
More Related Videos
04:54Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
Published on: June 2, 2023
1.4K
10:30Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
Published on: April 1, 2019
9.0K
Related Concept Videos
01:25Metabolic Rate
431
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
431
01:26Activation Energy
80.0K
Activation energy is the minimum amount of energy necessary for a chemical reaction to move forward. The higher the activation energy, the slower the rate of the reaction. However, adding heat to the reaction will increase the rate, since it causes molecules to move faster and increase the likelihood that molecules will collide. The collision and breaking of bonds represents the uphill phase of a reaction and generates the transition state. The transition state is an unstable high-energy state...
80.0K
01:24Overview of Lipid Metabolism
1.9K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.9K
01:25Body Temperature
1.1K
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
1.1K
01:26Thermoregulation
1.1K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
1.1K
01:19Regulation of Metabolism
9.6K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
9.6K