Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

747
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
747
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

5.4K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of microvascular invasion in hepatocellular carcinoma using contrast-enhanced ultrasound and deep learning.

Nature communications·2026
Same author

Spatial signal distribution learning for high-resolution 3D system matrix calibration in magnetic particle imaging.

Physics in medicine and biology·2026
Same author

A compact low-power magnetic particle imaging scanner based on a permanent-magnet field-free-line generator with high gradient.

The Review of scientific instruments·2026
Same author

Breaking the Trade-off in MPI-Guided Magnetic Hyperthermia by Tailoring the Dynamic Magnetization of Magnetic Nanoparticles via Site-Selective Trace Doping.

Journal of the American Chemical Society·2026
Same author

TSMPI-Net: a time-series generative adversarial network for short-frame-interval magnetic particle imaging.

Physics in medicine and biology·2026
Same author

STimulated emission depletion (STED) magnetic particle imaging.

Medical physics·2025

Related Experiment Video

Updated: Aug 5, 2025

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.7K

Improved Quantitative Analysis Method for Magnetic Particle Imaging Based on Deblurring and Region Scalable Fitting.

Lu Wang1,2, Yan Huang1,2, Yishen Zhao1,2

  • 1School of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.

Molecular Imaging and Biology
|March 27, 2023
PubMed
Summary

This study introduces a new method for Magnetic Particle Imaging (MPI) to improve image analysis. The DeRSF technique enhances tracer quantification and segmentation accuracy for biomedical applications.

Keywords:
DeblurMagnetic particle imaging (MPI)QuantificationRegion scalable fitting (RSF)

More Related Videos

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
07:42

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

Published on: July 20, 2022

2.8K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.6K

Related Experiment Videos

Last Updated: Aug 5, 2025

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.7K
Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
07:42

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

Published on: July 20, 2022

2.8K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.6K

Area of Science:

  • Biomedical Imaging
  • Medical Physics
  • Image Processing

Background:

  • Magnetic Particle Imaging (MPI) offers high sensitivity and no radiation for biomedical imaging.
  • Anisotropic point spread function (PSF) in MPI poses challenges for accurate image analysis.
  • Precise quantitative evaluation of MPI in vivo requires improved image restoration and segmentation.

Purpose of the Study:

  • To develop an advanced MPI image restoring and segmentation method.
  • To enable more accurate quantitative evaluation of magnetic particle imaging in vivo.
  • To address the challenges posed by anisotropic PSF in MPI.

Main Methods:

  • Proposed the DeRSF method combining deblurring and region scalable fitting (RSF).
  • Established a uniform erosion and scaling criterion for segmentation correction.
  • Developed a calibration curve for iron quantification using MPI tracer concentrations.

Main Results:

  • Achieved improved segmentation performance with a mean Dice coefficient of 0.86 in phantom imaging.
  • Demonstrated accurate mapping and quantification of tracer distribution.
  • Realized in vivo iron quantification with a minimal error of 5.50%.

Conclusions:

  • The DeRSF method successfully enhances MPI quantitative analysis.
  • The method provides accurate quantitative results across various shapes and concentrations in phantom and in vivo data.
  • This work establishes a foundation for advanced biomedical studies using MPI.