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Risperidone-Induced Sexual Dysfunction Case Report
Gregory J Cichon1, Syed F Qadri1
1Psychiatry, Creighton University School of Medicine, Omaha, USA.
Cureus
|March 28, 2023
Summary
Antipsychotic medication can cause sexual side effects, impacting treatment adherence. Switching from risperidone to lurasidone may resolve these issues, improving patient outcomes in bipolar disorder.
Area of Science:
- Psychiatry
- Pharmacology
Background:
- Treatment-emergent sexual dysfunction (TESD) is a common adverse effect of antipsychotics, notably risperidone.
- This can lead to noncompliance in patients with psychiatric disorders, impacting treatment efficacy.
Observation:
- A 55-year-old male with bipolar disorder type 1 discontinued risperidone due to sexual side effects (reduced libido, anejaculation).
- He was subsequently treated with lurasidone during inpatient psychiatric care.
Findings:
- The patient's psychiatric symptoms improved on lurasidone.
- He experienced resolution of sexual dysfunction and remained symptom-free during six months of outpatient follow-up.
Implications:
- This case suggests lurasidone as a potential alternative for patients experiencing risperidone-induced sexual dysfunction.
- Further research is needed to confirm lurasidone's efficacy and tolerability for TESD and address patient reluctance to discuss sexual side effects.
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