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Prevalence of Left Ventricular Diastolic Dysfunction in Patients with Essential Hypertension

Srijana Paudel1, Mani Prasad Gautam1, Yadu Nath Baral1

  • 1National Academy of Medical Sciences, Kathmandu, Nepal.

Journal of Nepal Health Research Council
|March 28, 2023
PubMed

Insights

Left ventricular diastolic dysfunction (LVDD) affects 33.8% of hypertensive patients. Longer hypertension duration, older age, and higher BMI are linked to LVDD, highlighting the need for early management in essential hypertension.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Diastolic Function

Background:

  • Left Ventricular Diastolic Dysfunction (LVDD) is a key factor linking hypertension and heart failure, especially in heart failure with preserved ejection fraction.
  • Understanding LVDD prevalence and associated factors in essential hypertension is crucial for patient management.

Purpose of the Study:

  • To determine the prevalence of LVDD in patients with essential hypertension.
  • To identify clinical parameters associated with LVDD in this population.

Main Methods:

  • A hospital-based cross-sectional study was conducted on 68 hypertensive patients.
  • Echocardiography was used to assess LVDD, with results compared to clinical parameters like age, sex, BMI, and dyslipidemia.

Main Results:

  • The prevalence of LVDD was 33.8% among essential hypertensive patients.
  • Hypertension duration over five years (OR 9.14) was significantly associated with LVDD.
  • Age and Body Mass Index (BMI) showed a statistically significant correlation with LVDD (P<0.05).

Conclusions:

  • LVDD is prevalent in patients with essential hypertension.
  • Age, BMI, dyslipidemia, and hypertension duration are significant factors associated with LVDD.
Abstract

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