Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Aug 5, 2025

Endoscopic Cholesteatoma Surgery
08:47

Endoscopic Cholesteatoma Surgery

Published on: January 19, 2022

10.3K

Primary Ear Reconstruction Using Cadaveric Costal Cartilage.

Jose F Palacios1, Nissim Hazkour2, Emma Robinson1

  • 1From the Zucker School of Medicine at Hofstra/Northwell, Hempstead.

Annals of Plastic Surgery
|March 28, 2023
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From topography to connectome: Towards an integrated understanding of the resting brain.

bioRxiv : the preprint server for biology·2026
Same author

What's New in Biologics.

The Journal of bone and joint surgery. American volume·2026
Same author

PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy.

Neoplasia (New York, N.Y.)·2026
Same author

Sex differences in the enjoyment of enrichment: affective bias testing confirms female rats prefer more playful and less vigorous tickling.

Biology letters·2026
Same author

HLA class I signal peptide variation predicts strength of NKG2A<sup>+</sup> NK cell response to missing-self and risk of human disease.

Nature immunology·2026
Same author

Respiratory function in Becker muscular dystrophy: a comprehensive longitudinal study.

Journal of neurology, neurosurgery, and psychiatry·2026

Allogeneic cadaveric costal cartilage shows promise for ear reconstruction in microtia patients. While generally safe, risks like infection and resorption require monitoring for long-term success.

Area of Science:

  • Plastic Surgery
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Allogeneic cadaveric costal cartilage is a common graft material for nasal reconstruction.
  • Its application in total ear reconstruction for microtia is not well-documented.
  • This study explores its novel use in auricular framework construction.

Purpose of the Study:

  • To describe the novel use of cadaveric cartilage for auricular framework construction in microtia reconstruction.
  • To review preliminary histologic findings of this application.
  • To evaluate the safety and efficacy of allogeneic costal cartilage in ear reconstruction.

Main Methods:

  • A case series of 12 ear reconstructions using cadaveric costal cartilage in 11 patients (ages 4-25) with microtia (Types III and IV).

More Related Videos

Author Spotlight: Advancing Endoscopic Ossiculoplasty &#8211; Techniques, Innovations, and Practical Guidance for Clinical Integration
09:07

Author Spotlight: Advancing Endoscopic Ossiculoplasty – Techniques, Innovations, and Practical Guidance for Clinical Integration

Published on: January 26, 2024

2.5K
Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique
07:06

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

3.9K

Related Experiment Videos

Last Updated: Aug 5, 2025

Endoscopic Cholesteatoma Surgery
08:47

Endoscopic Cholesteatoma Surgery

Published on: January 19, 2022

10.3K
Author Spotlight: Advancing Endoscopic Ossiculoplasty &#8211; Techniques, Innovations, and Practical Guidance for Clinical Integration
09:07

Author Spotlight: Advancing Endoscopic Ossiculoplasty – Techniques, Innovations, and Practical Guidance for Clinical Integration

Published on: January 26, 2024

2.5K
Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique
07:06

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

3.9K
  • Patients were monitored for surgical site infection, skin necrosis, cartilage resorption, and exposure.
  • Histologic analysis of cartilage samples obtained 1 year post-implantation was performed.
  • Main Results:

    • No significant cartilage warping observed in 12 procedures.
    • Two cases of minor construct exposure were successfully managed.
    • Two surgical site infections occurred, one leading to resorption and framework replacement.
    • Histology revealed viable chondrocytes with no signs of immune rejection or inflammation.

    Conclusions:

    • Cadaveric costal cartilage is a viable alternative for auricular frameworks in microtia reconstruction.
    • Potential risks include infection-related resorption and construct exposure.
    • Further long-term studies with larger cohorts are necessary to confirm efficacy.