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Intraocular pressure variation from ocular compression in low and high myopia
1School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong.
Clinical & Experimental Optometry
|March 28, 2023
Summary
Intraocular pressure (IOP) changes during ocular compression differ between low and high myopia. Low myopes exhibit faster IOP decay and recovery, suggesting distinct aqueous humor dynamics.
Area of Science:
- Ophthalmology
- Physiology
Background:
- Ocular compression monitoring of intraocular pressure (IOP) changes offers insights into aqueous humor dynamics.
- Previous studies focused on lamina cribrosa deformation and single post-compression IOP measurements, neglecting dynamic IOP changes.
Purpose of the Study:
- To evaluate intraocular pressure (IOP) changes during and after acute ocular compression.
- To compare these IOP dynamics between individuals with low myopia and high myopia.
Main Methods:
- Age-matched cohorts of low and high myopes underwent ocular compression for 2 minutes.
- Intraocular pressure (IOP) was measured at baseline, during compression at 30-second intervals, and during a 10-minute recovery phase using rebound tonometry.
Main Results:
- Both low and high myopes showed similar baseline IOP and peak IOP during compression.
- Low myopes demonstrated a significantly faster rate of IOP decay during compression (-3.24 mmHg/min vs. -2.58 mmHg/min).
- Following compression release, low myopes' IOP returned to baseline faster (360s) than high myopes (510s).
Conclusions:
- Single post-compression IOP measurements may underestimate the full impact of IOP fluctuations.
- Dynamic IOP monitoring during and after ocular compression provides valuable data on aqueous humor outflow facilities.
- Differences in IOP response highlight potential variations in ocular biomechanics between low and high myopia.
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