Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphological aspects, classification and epidemiology of emphysema.

J H Dijkman

    Bulletin Europeen De Physiopathologie Respiratoire
    |January 1, 1986
    PubMed
    Summary

    Emphysema causes chronic airflow obstruction, but standard tests can't distinguish it from bronchial disease. Post-mortem studies reveal age, smoking, sex, and environment impact emphysema prevalence.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Diagnostic image (4)].

    Nederlands tijdschrift voor geneeskunde·2000
    Same author

    A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy.

    American journal of respiratory and critical care medicine·1999
    Same author

    [Open lung biopsy in seriously ill patients with undiagnosed lung infiltrates].

    Nederlands tijdschrift voor geneeskunde·1999
    Same author

    Cigarette smoking and pulmonary diffusion defects in rheumatoid arthritis.

    Rheumatology international·1998
    Same author

    Ozone-induced airway hyperresponsiveness in patients with asthma: role of neutrophil-derived serine proteinases.

    Free radical biology & medicine·1998
    Same author

    Effect of neutrophil serine proteinases and defensins on lung epithelial cells: modulation of cytotoxicity and IL-8 production.

    Journal of leukocyte biology·1997

    Area of Science:

    • Pulmonary Medicine
    • Pathology

    Background:

    • Emphysema is an anatomically defined disorder causing chronic airflow obstruction.
    • Airflow obstruction can also stem from bronchial diseases, complicating diagnosis.
    • Current pulmonary function tests and standard chest radiology lack specificity for emphysema detection.

    Purpose of the Study:

    • To highlight the diagnostic limitations of current methods for identifying emphysema.
    • To underscore the importance of post-mortem quantitation in understanding emphysema prevalence factors.

    Main Methods:

    • Review of diagnostic limitations of pulmonary function tests and standard thoracic radiology.
    • Analysis of post-mortem studies where emphysema was quantitatively assessed.

    Main Results:

    • Pulmonary function tests do not differentiate emphysema from other causes of airflow obstruction.
    • Standard radiology is only indicative of advanced emphysema.
    • Post-mortem quantitation identified age, smoking, sex, and environmental factors as significant in emphysema prevalence.

    Conclusions:

    • Accurate differentiation of emphysema from other obstructive lung diseases remains a challenge with current clinical tools.
    • Post-mortem analysis provides crucial insights into the multifactorial nature of emphysema prevalence.

    Related Experiment Videos