Irrigation in Endodontics: Polyhexanide Is a Promising Antibacterial Polymer in Root Canal Treatment

Area of Science:

• Dentistry
• Endodontics
• Microbiology

Background:

• Chronic apical periodontitis is a prevalent dental condition requiring effective management.
• Systematizing data on endodontic irrigation solutions is crucial for treatment advancement.
• Polyhexanide-based antiseptics show potential for enhancing endodontic treatment success.

Purpose of the Study:

• To review and systematize data on irrigation solutions for endodontic treatment.
• To evaluate the efficacy of polyhexanide as an antiseptic for root canal irrigation.
• To assess the role of polyhexanide in managing chronic apical periodontitis.

Main Methods:

• A systematic review of English-language research and meta-analyses.
• Literature search conducted using Google Scholar and PubMed databases.
• Inclusion of 68 articles after initial identification of 180 sources.

Main Results:

• Identified 180 relevant literary sources during the initial search.
• Excluded publications not meeting specific search criteria.
• Finalized a systematic review comprising 68 selected articles.

Conclusions:

• Polyhexanide demonstrates significant promise as an irrigant for infected root canals.
• The potent antibacterial activity of polyhexanide is effective against pathogens causing apical periodontitis.
• Polyhexanide offers a viable solution for improving endodontic treatment efficacy.