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Hydrogels-A Promising Materials for 3D Printing Technology.

Gobi Saravanan Kaliaraj1, Dilip Kumar Shanmugam1, Arish Dasan2

  • 1Centre for Nanoscience and Nanotechnology, Sathyabama Institute of Science and Technology, Chennai 600 119, India.

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Summary

Hydrogels offer versatile applications in medicine and beyond due to tailored properties. This review explores hydrogel classifications, enhancement techniques, and their potential in 3D bioprinting and drug delivery systems.

Keywords:
pH-sensitive hydrogelpolymer hydrogelsregenerative medicinethermo-sensitive hydrogelwound dressing

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Area of Science:

  • Materials Science
  • Biotechnology
  • Chemical Engineering

Background:

  • Hydrogels are versatile polymeric networks capable of absorbing large amounts of water.
  • Significant research has advanced hydrogel applications across pharmaceuticals, biotechnology, agriculture, biosensors, and cosmetics.
  • Functional and structural design is crucial for tailoring hydrogel physicochemical properties and cell signaling interactions.

Purpose of the Study:

  • To review hydrogel classifications and their inherent limitations.
  • To explore methods for enhancing hydrogel physical, mechanical, and biological properties.
  • To discuss recent advances in functional hydrogels for biomedical applications, including 3D bioprinting and drug delivery.

Main Methods:

  • Literature review of hydrogel classifications and properties.
  • Analysis of techniques for hydrogel modification using organic and inorganic admixtures.
  • Examination of recent developments in responsive and drug-delivery hydrogels.

Main Results:

  • Hydrogels exhibit diverse classifications with specific limitations.
  • Admixing organic and inorganic materials effectively improves hydrogel properties.
  • 3D printing with hydrogels shows promise for creating functional living tissue structures.
  • Functional hydrogels, including photo- and pH-responsive types, demonstrate significant potential in drug delivery.

Conclusions:

  • Hydrogel design is key to unlocking their full application potential.
  • Enhancement techniques are vital for overcoming hydrogel limitations.
  • Hydrogels are poised to revolutionize 3D bioprinting and advanced biomedical therapies.