Related Experiment Video
Updated: Aug 5, 2025

08:27
Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
Published on: March 3, 2023
1.0K
Central and Peripheral Ocular High-Order Aberrations and Their Relationship with Accommodation and Refractive Error:
Jessica Gomes1, Kishor Sapkota1, Sandra Franco1
1Centre of Physics, University of Minho, 4710-057 Braga, Portugal.
Vision (Basel, Switzerland)
|March 28, 2023
Summary
High-order aberrations (HOAs) change with accommodation, pupil size, and age, impacting image quality. These optical defects are linked to refractive error progression, particularly myopia.
Area of Science:
- Ophthalmology
- Optical Engineering
- Physiological Optics
Background:
- High-order aberrations (HOAs) are optical defects affecting visual quality.
- HOAs are dynamic, varying with pupil diameter, age, and accommodation.
- Lens shape and position changes are primary drivers of aberrations during accommodation.
Purpose of the Study:
- To investigate the relationship between high-order aberrations and accommodation.
- To explore the influence of refractive error on central and peripheral HOAs during accommodation.
- To understand the role of HOAs in refractive error progression, especially myopia.
Main Methods:
- Ophthalmic aberrometry to measure central and peripheral HOAs.
- Dynamic measurements during accommodative tasks.
- Analysis of HOA changes in relation to refractive error status.
Main Results:
- Primary spherical aberration (Z(4.0)) shows a strong correlation with accommodation.
- Central and peripheral HOAs exhibit distinct variations based on refractive error.
- Accommodative HOA changes differ between refractive error groups.
Conclusions:
- HOAs are closely linked to the accommodative system and influence its accuracy.
- Variations in HOAs, particularly in the periphery, may impact eye growth and myopia progression.
- Understanding HOA dynamics is crucial for managing refractive errors and myopia.
Related Concept Videos
Focusing of Light in the Eye
3.0K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.0K
Glaucoma: Overview
657
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
657
Accessory Structures of the Eye
1.7K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.7K
Angle Closure Glaucoma: Treatment
591
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
591
Influence of Earth's Curvature and Atmospheric Refraction on Leveling
171
During leveling, the Earth's curvature and atmospheric refraction introduce deviations in the line of sight from a true horizontal reference. When the line of sight is leveled, it remains perpendicular to the plumb line only at a single point. Beyond this, it deviates due to the Earth’s curvature, represented by the correction C. For a sight distance D, the deviation can be derived using the relationship:This relationship shows that the deviation increases quadratically with distance.
171
Open Angle Glaucoma: Treatment
509
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
509

