Related Experiment Video
Updated: Aug 5, 2025
Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
Published on: May 27, 2011
Cell-Based Biomaterials for Coronavirus Disease 2019 Prevention and Therapy
Chuyu Li1, Chenguang Wang1, Hai-Yan Xie1
1School of Medical Technology, Beijing Institute of Technology, Beijing, 100081, P. R. China.
Abstract:
Coronavirus disease 2019 (COVID-19) continues to threaten human health, economic development, and national security. Although many vaccines and drugs have been explored to fight against the major pandemic, their efficacy and safety still need to be improved. Cell-based biomaterials, especially living cells, extracellular vesicles, and cell membranes, offer great potential in preventing and treating COVID-19 owing to their versatility and unique biological functions. In this review, the characteristics and functions of cell-based biomaterials and their biological applications in COVID-19 prevention and therapy are described. First the pathological features of COVID-19 are summarized, providing enlightenment on how to fight against COVID-19. Next, the classification, organization structure, characteristics, and functions of cell-based biomaterials are focused on. Finally, the progress of cell-based biomaterials in overcoming COVID-19 in different aspects, including the prevention of viral infection, inhibition of viral proliferation, anti-inflammation, tissue repair, and alleviation of lymphopenia are comprehensively described. At the end of this review, a look forward to the challenges of this aspect is presented.
Insights
Cell-based biomaterials show promise for preventing and treating Coronavirus disease 2019 (COVID-19) by offering unique biological functions. This review details their characteristics and applications in combating the pandemic.
Area of Science:
- Biomaterials Science
- Immunology
- Infectious Diseases
Background:
- Coronavirus disease 2019 (COVID-19) poses significant global health and economic threats.
- Current vaccines and drugs for COVID-19 require improved efficacy and safety.
- Cell-based biomaterials present a promising avenue for novel COVID-19 therapeutics.
Purpose of the Study:
- To review the characteristics and functions of cell-based biomaterials.
- To explore the biological applications of cell-based biomaterials in COVID-19 prevention and therapy.
- To summarize the pathological features of COVID-19 to guide therapeutic strategies.
Main Methods:
- Literature review of cell-based biomaterials and their role in COVID-19.
- Analysis of pathological features of COVID-19.
- Classification and functional characterization of cell-based biomaterials (living cells, extracellular vesicles, cell membranes).
Main Results:
- Cell-based biomaterials exhibit versatility and unique biological functions applicable to COVID-19.
- Applications include prevention of viral infection, inhibition of viral proliferation, anti-inflammation, tissue repair, and alleviation of lymphopenia.
- Progress in utilizing these materials against various aspects of COVID-19 is comprehensively described.
Conclusions:
- Cell-based biomaterials offer significant potential for developing advanced strategies against COVID-19.
- Further research is needed to address the challenges and optimize the use of these biomaterials.
- This review provides a forward-looking perspective on the future of cell-based biomaterials in pandemic control.
More Related Videos
Related Concept Videos
01:19Mesenchymal Stem Cells
01:21Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...