Related Experiment Videos
In vitro activity of sulphonamides as a function of their molar refractivity
Chemotherapy
|January 1, 1979
Abstract:
A significnat correlation has been found between the in vitro activity of 16 commonly employed sulphonamides and their molar refractivity. The molar refractivity has been shown to be a superior parameter for the description of the activity of sulphonamides than the sum of electronegativities of atoms making up a heterocyclic substituent in the sulphonamide molecule and molecular weight of the substituent.