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Neurofilament Levels in Dendritic Spines Associate with Synaptic Status.

Clara-Marie Gürth1,2, Maria Augusta do Rego Barros Fernandes Lima1, Victor Macarrón Palacios1,2

  • 1Department of Optical Nanoscopy, Max Planck Institute for Medical Research, 69120 Heidelberg, Germany.

Cells
|March 29, 2023
PubMed
Summary

Neurofilament light (NFL) is the most abundant postsynaptic isoform, correlating with synaptic strength and activity. This finding offers new insights into neurofilament regulation and synaptopathies.

Keywords:
STED nanoscopydendritic spinesneurofilamentssynapses

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