Ultrasound Imaging for Diaphragm Function in a Population of Healthy Infants: A Short Observational Report

Danilo Buonsenso1,2, Francesco Mariani1, Rosa Morello1

  • 1Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.

Insights

This study establishes normal diaphragm ultrasound parameters for healthy infants up to six months old. These findings provide crucial reference data for pediatric diaphragm assessments.

Area of Science:

  • Pediatric Pulmonology
  • Medical Imaging
  • Neonatology

Background:

  • Diaphragm ultrasound is a growing diagnostic tool in adult and pediatric medicine.
  • Normal diaphragm ultrasound values for healthy infants are not well-established.
  • This study addresses the need for normative data in early life.

Purpose of the Study:

  • To define normal diaphragm ultrasound characteristics in healthy infants during the first six months of life.
  • To establish reference values for diaphragm thickness and function in neonates and young children.

Main Methods:

  • Prospective observational pilot study involving healthy neonates followed for six months.
  • Five assessments were conducted, measuring diaphragm thickness at end expiration (TEE) and end inspiration (TEI).
  • Calculated thickening fraction (TF) using two different formulas.

Main Results:

  • 37 infants were enrolled, with detailed demographic information provided.
  • Normal values for TEE, TEI, and TF were determined at each assessment time point.
  • The study provides the first reference data for diaphragm ultrasound parameters in healthy infants.

Conclusions:

  • This research offers essential normative data for diaphragm ultrasound in healthy infants.
  • The findings will support future pediatric studies investigating diaphragm physiology and pathology.
  • Establishes a baseline for evaluating abnormal diaphragm function in infants.
Abstract

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