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Is It Time to Integrate Frailty Assessment in Onconephrology?
Henry H L Wu1, Rajkumar Chinnadurai2, Robert J Walker3
1Renal Research Laboratory, Kolling Institute of Medical Research, Royal North Shore Hospital, The University of Sydney, Sydney, NSW 2065, Australia.
Cancers
|March 29, 2023
Summary
Onconephrology addresses kidney issues in cancer patients, especially older adults with frailty and chronic kidney disease (CKD). Integrating frailty assessment is crucial for tailored cancer care and improved patient outcomes.
Area of Science:
- Onconephrology
- Nephrology
- Geriatrics
- Oncology
Background:
- Onconephrology integrates kidney disease and cancer care, addressing concurrent CKD, acute kidney injury, and treatment toxicity.
- The growing elderly population presents challenges, as many have CKD and are at high risk for malignancies.
- Frailty assessment is established in kidney disease but underexplored in onconephrology.
Purpose of the Study:
- To define and operationalize frailty within the context of onconephrology.
- To review current frailty assessment methods in onconephrology.
- To discuss future directions for integrating frailty into onconephrology patient management.
Main Methods:
- Literature review on frailty assessment tools and their application in onconephrology.
- Evaluation of the significance of frailty in older adults with cancer and kidney disease.
- Discussion of existing data and identification of knowledge gaps.
Main Results:
- Frailty is a significant factor in older adults with CKD and cancer.
- Current frailty assessment in onconephrology is limited, with emerging data.
- Integration of frailty assessment can guide management and prognostication.
Conclusions:
- Further research is needed to understand the impact of frailty in onconephrology.
- Developing and implementing frailty assessment tools is essential for personalized cancer care in kidney patients.
- Optimizing patient management requires integrating frailty into onconephrology strategies.
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