Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Isolation01:24

DNA Isolation

39.6K
DNA isolation protocols can be fast and straightforward or complex and time-consuming depending on the type and quality of DNA required for further processing. For example, plasmid DNA extraction is a bit more complicated than genomic DNA extraction because of the need for an appropriate lysis method to separate plasmid DNA from gDNA during isolation. However, for specific applications, such as long-range DNA sequencing that require a good yield of high- quality DNA samples, we need to follow...
39.6K
DNA Agarose Gel Electrophoresis02:35

DNA Agarose Gel Electrophoresis

97.7K
Agarose gel electrophoresis is a laboratory technique commonly used to separate DNA fragments by size. However, it can also be used to isolate and purify DNA fragments using a gel extraction protocol.
Gel extraction follows five major steps: running gel electrophoresis to separate fragments, isolating the individual bands, extracting DNA from those bands, and removing the dye and salts from the extracted mixture to obtain pure DNA.
In cloning experiments, both the insert and vector DNA...
97.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Small pieces make the big picture: the etiology of the relationship between executive functions and personality traits.

BMC psychology·2025
Same author

Personality and <i>COMT</i> gene: molecular-genetic and epigenetic associations with NEO-PI-R personality domains and facets in monozygotic twins.

Frontiers in genetics·2024
Same author

Introduction to the JFS Special Section on Disaster Victim Identification (DVI).

Journal of forensic sciences·2024
Same author

Global survey on evaluative reporting on DNA evidence with regard to activity-level propositions.

Journal of forensic sciences·2024
Same author

Differences in <i>MB-COMT</i> DNA methylation in monozygotic twins on phenotypic indicators of impulsivity.

Frontiers in genetics·2023
Same author

American forensic DNA practitioners' opinion on activity level evaluative reporting.

Journal of forensic sciences·2022

Related Experiment Video

Updated: Aug 5, 2025

DNA Extraction from Paraffin Embedded Material for Genetic and Epigenetic Analyses
13:32

DNA Extraction from Paraffin Embedded Material for Genetic and Epigenetic Analyses

Published on: March 26, 2011

56.5K

Development of Improved DNA Collection and Extraction Methods for Handled Documents.

Ashley G Morgan1, Mechthild Prinz2

  • 1Department of Forensic Science, University of New Haven, 300 Boston Post Road, West Haven, CT 06516, USA.

Genes
|March 29, 2023
PubMed
Summary
This summary is machine-generated.

Researchers explored DNA recovery from handwritten documents, finding vacuum sampling and Chelex-Tween extraction effective. Touch DNA deposits on paper remained stable over an 11-month period.

Keywords:
fingermarkspaper evidencesample collectiontouch DNA

More Related Videos

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic &#8216;Touch DNA&#8217; Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

15.8K
Filtration Isolation of Nucleic Acids: A Simple and Rapid DNA Extraction Method
07:56

Filtration Isolation of Nucleic Acids: A Simple and Rapid DNA Extraction Method

Published on: August 6, 2016

18.2K

Related Experiment Videos

Last Updated: Aug 5, 2025

DNA Extraction from Paraffin Embedded Material for Genetic and Epigenetic Analyses
13:32

DNA Extraction from Paraffin Embedded Material for Genetic and Epigenetic Analyses

Published on: March 26, 2011

56.5K
Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic &#8216;Touch DNA&#8217; Evidence
11:49

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

Published on: March 9, 2015

15.8K
Filtration Isolation of Nucleic Acids: A Simple and Rapid DNA Extraction Method
07:56

Filtration Isolation of Nucleic Acids: A Simple and Rapid DNA Extraction Method

Published on: August 6, 2016

18.2K

Area of Science:

  • Forensic Science
  • Molecular Biology
  • Document Examination

Background:

  • Handwritten documents can contain valuable DNA evidence.
  • Current crime lab practices often overlook DNA extraction from paper.
  • DNA recovery methods must not compromise other forensic analyses like latent prints.

Purpose of the Study:

  • To evaluate DNA recovery techniques from fingermarks on paper.
  • To compare different DNA extraction methods for paper samples.
  • To assess the stability of touch DNA on paper over time.

Main Methods:

  • Fingermarks on paper were sampled using flocked swabs, cutting, and dry vacuuming.
  • Two distinct DNA extraction methods were compared.
  • The stability of touch DNA deposits was monitored over an 11-month period.

Main Results:

  • DNA yields were generally low across all tested methods.
  • The dry vacuum sampling method combined with Chelex-Tween extraction proved useful.
  • No significant degradation of DNA deposits on paper was observed within the 11-month study.

Conclusions:

  • DNA can be successfully recovered from fingermarks on paper.
  • Dry vacuum sampling and Chelex-Tween extraction are recommended for paper DNA analysis.
  • Touch DNA on paper exhibits stability over extended periods, aiding forensic investigations.