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Purinergic P2 Receptors: Structure and Function 2.0
1Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic.
This Special Issue explores purinergic P2 receptors, building on previous research into their structure and function. It delves into the latest molecular insights and therapeutic applications of these critical cellular signaling components.
Area of Science:
- Molecular Biology
- Pharmacology
- Biochemistry
Background:
- Purinergic signaling, mediated by extracellular nucleotides and nucleosides, plays a vital role in numerous physiological and pathological processes.
- P2 receptors, a key component of purinergic signaling, are transmembrane proteins activated by various extracellular adenosine and uridine nucleotides.
- Dysregulation of P2 receptor function is implicated in a wide range of diseases, including inflammation, pain, cancer, and cardiovascular disorders.
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