Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

6.1K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
6.1K
Burn Injuries01:22

Burn Injuries

2.6K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
2.6K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

5.3K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
5.3K
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

4.1K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
4.1K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

13
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
13

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Covalently Functionalized Halloysite-Calixarene Nanotubes for Injectable Hydrogels: A Multicavity Platform for Hydrophobic Drug Delivery.

Pharmaceuticals (Basel, Switzerland)·2025
Same author

Design of halloysite nanotube-based nanomaterials for theranostic applications: fluorescent probes and chemodynamic activity.

Journal of materials chemistry. B·2025
Same author

Griffonia simplicifolia seeds extract rich in 5-hydroxy-L-tryptophan reduces infection and inflammation in a mouse model of vulvovaginal candidiasis.

The Journal of pharmacy and pharmacology·2025
Same author

Use of Ozone for Disinfection of PHARMODUCT<sup>®</sup> Automatic System for Antineoplastic Compounding.

Pharmaceuticals (Basel, Switzerland)·2025
Same author

Halloysite Nanotube-Based Delivery of Pyrazolo[3,4-<i>d</i>]pyrimidine Derivatives for Prostate and Bladder Cancer Treatment.

Pharmaceutics·2024
Same author

The Use of Organoclays as Excipient for Metformin Delivery: Experimental and Computational Study.

Molecules (Basel, Switzerland)·2024

Related Experiment Video

Updated: Aug 5, 2025

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

1.2K

Recent Approaches for Wound Treatment.

Cinzia Pagano1, César Antonio Viseras Iborra2, Luana Perioli1

  • 1Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.

International Journal of Molecular Sciences
|March 29, 2023
PubMed
Summary

Wound healing remains a global health challenge. This study explores novel therapeutic strategies to improve wound repair and reduce complications.

More Related Videos

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

486
Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

674

Related Experiment Videos

Last Updated: Aug 5, 2025

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

1.2K
A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

486
Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model
07:56

Digital Planimetry for Assessing Wound Closure Kinetics in a Mouse Model

Published on: January 10, 2025

674

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Wound Care

Background:

  • Chronic wounds affect millions globally, leading to significant morbidity and healthcare costs.
  • Current treatments for wound healing often face limitations in efficacy and patient outcomes.
  • Advanced therapeutic approaches are crucial for addressing the complexities of wound repair.

Discussion:

  • Investigating innovative biomaterials and drug delivery systems for enhanced wound healing.
  • Analyzing the role of cellular signaling pathways in promoting tissue regeneration.
  • Evaluating the potential of regenerative medicine techniques in wound management.

Key Insights:

  • Novel therapeutic strategies show promise in accelerating wound closure and improving tissue regeneration.
  • Understanding the molecular mechanisms underlying wound healing is key to developing effective treatments.
  • Multidisciplinary approaches combining biomaterials and regenerative medicine offer a new paradigm for wound care.

Outlook:

  • Future research will focus on clinical translation of these advanced wound healing strategies.
  • Development of personalized wound treatment plans based on patient-specific factors.
  • Reducing the global burden of wounds through innovative and accessible therapies.