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A Summary on Tuberculosis Vaccine Development-Where to Go?
Fan Jiang1,2, Tiehui Sun3, Peng Cheng1
1Tuberculosis Prevention and Control Key Laboratory/Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Senior Department of Tuberculosis, The 8th Medical Center of PLA General Hospital, Beijing 100091, China.
Journal of Personalized Medicine
|March 29, 2023
Summary
This bibliometric analysis reveals a significant increase in tuberculosis (TB) vaccine research over 20 years. Future TB vaccine development will focus on host-pathogen interactions.
Area of Science:
- Immunology
- Infectious Diseases
- Vaccinology
Background:
- Tuberculosis (TB) remains a significant global infectious disease.
- Vaccination is crucial for TB prevention and control.
- Bibliometric analysis of TB vaccine research progress is limited.
Purpose of the Study:
- To systematically analyze TB vaccine research over the past two decades.
- To identify current research priorities and future directions in TB vaccine development.
Main Methods:
- Bibliometric analysis of publications from the Science Citation Index Expanded (SCI-E) database.
- Utilized VOSviewer, CiteSpace, and Bibliometrix for data visualization and analysis.
- Statistical analysis performed using GraphPad Prism and Microsoft Excel.
Main Results:
- 7960 publications on TB vaccines identified between 2002 and 2022.
- The United States, United Kingdom, and China are leading contributors.
- Future research trends indicate a focus on host-pathogen interaction mechanisms.
Conclusions:
- TB vaccine research has shown substantial growth over the last two decades.
- Developed nations lead TB vaccine research, with developing countries rapidly advancing.
- Future TB vaccine development will likely concentrate on molecular mechanisms of host-pathogen interactions.
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