Related Experiment Video
Updated: Aug 5, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
Published on: November 1, 2015
The global epidemiology of SLE: narrowing the knowledge gaps
Megan R W Barber1, Titilola Falasinnu2, Rosalind Ramsey-Goldman3
1Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Abstract:
SLE is a global health concern that unevenly affects certain ethnic/racial groups. Individuals of Asian, Black, Hispanic and Indigenous ethnicity/race are amongst those who experience increased prevalence, incidence, morbidity and mortality. Population-based surveillance studies from many regions are few and often still in nascent stages. Many of these areas are challenged by restricted access to diagnostics and therapeutics. Without accurately capturing the worldwide burden and distribution of SLE, appropriately dedicating resources to improve global SLE outcomes may be challenging. This review discusses recent SLE epidemiological studies, highlighting the challenges and emerging opportunities in low- and middle-income countries. We suggest means of closing these gaps to better address the global health need in SLE.
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Introduction to Epidemiology
Bias in Epidemiological Studies
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Single Nucleotide Polymorphisms-SNPs
Confounding in Epidemiological Studies

