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Updated: Aug 5, 2025

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Published on: May 22, 2019
Associations between posttraumatic stress and stroke: A systematic review and meta-analysis
Hely D Nanavati1, Andrea Arevalo2, Adeel A Memon3
1Department of Epidemiology, School of Public Health, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Posttraumatic stress disorder (PTSD) is linked to a significantly higher risk of stroke. This meta-analysis confirms that individuals with PTSD face a 59% increased likelihood of experiencing a stroke.
Area of Science:
- Neuroscience and Behavioral Science
- Cardiovascular Health
- Psychiatry
Background:
- Posttraumatic stress disorder (PTSD) is a mental health condition that can arise after experiencing or witnessing a traumatic event.
- Emerging evidence suggests a potential link between PTSD and cardiovascular diseases, including stroke.
- Systematic reviews and meta-analyses are crucial for synthesizing existing research on this association.
Conclusions:
- The findings strongly suggest that posttraumatic stress disorder is associated with an increased risk of stroke.
- Further research is warranted to elucidate the potential causal mechanisms underlying the PTSD-stroke association.
- This highlights the importance of considering mental health in cardiovascular risk assessment and prevention strategies.
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