The evolving field of regenerative aesthetics

Area of Science:

• Regenerative Medicine
• Aesthetics
• Tissue Engineering

Background:

• Regenerative aesthetics (RA) is an emerging field derived from regenerative medicine (RM).
• RA focuses on restoring youthful properties to aging tissues, distinct from RM's focus on repairing injured or diseased tissues.
• Understanding the aging tissue environment is critical for RA development.

Purpose of the Study:

• To establish key concepts, definitions, and foundations for regenerative aesthetic approaches.
• To review current evidence supporting RA treatments.
• To introduce regenerative scaffolds, specifically calcium hydroxylapatite (CaHA), and discuss future directions.

Main Methods:

• Literature review of regenerative aesthetics principles and evidence.
• Analysis of the aging tissue microenvironment.
• Exploration of regenerative scaffold technologies, including CaHA.

Main Results:

• Regenerative aesthetics aims to rejuvenate aging tissues, differing from regenerative medicine's repair focus.
• The aging tissue environment presents unique challenges for aesthetic treatments.
• Regenerative scaffolds, such as CaHA, show promise in RA.

Conclusions:

• Regenerative aesthetics is an evolving subfield of regenerative medicine.
• Clear definitions and understanding of the aging tissue environment are vital for RA.
• Re-evaluation of evidence based on regenerative goals will advance the field.