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Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

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Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
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Troponins
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Lipidomics and Transcriptomics in Neurological Diseases
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Lipidomics, Acute Ischemic Stroke, Symptoms, and Outcomes: Observational Study Protocol.

Sarah R Martha, Alice Y Pen, Laura Stone McGuire

    Nursing Research
    |March 29, 2023
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    This study investigates lipidomic profiles in acute ischemic stroke patients over six months. Findings may reveal biomarkers linked to recovery and outcomes in those receiving reperfusion therapy versus those who did not.

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    Area of Science:

    • Biochemistry
    • Neurology
    • Metabolomics

    Background:

    • Acute ischemic stroke is a major global cause of death and disability.
    • Lipidomic profiling offers insights into stroke pathology and outcomes.
    • Understanding stroke recovery is crucial for improving patient care.

    Purpose of the Study:

    • To investigate the relationship between lipidomic signatures and patient recovery over six months post-stroke.
    • To compare these relationships in acute ischemic stroke patients who received reperfusion therapy versus those who did not.
    • To identify potential lipid biomarkers associated with stroke symptoms and outcomes.

    Main Methods:

    • Prospective cohort study with 104 acute ischemic stroke participants.
    • Two groups: reperfusion therapy (Group 1) and no reperfusion (Group 2).
    • Plasma and arterial blood samples collected for lipidomic analysis over six months; symptom and outcome data collected.

    Main Results:

    • The study will compare associations between plasma lipidomic biomarkers and clinical outcomes.
    • Cognitive, functional, and quality of life outcomes will be assessed over six months.
    • Differences in lipid profiles between reperfusion and non-reperfusion groups will be examined.

    Conclusions:

    • Lipidomic profiling may reveal biomarkers predicting stroke recovery and outcomes.
    • This research could inform personalized treatment strategies for acute ischemic stroke.
    • Understanding lipid changes post-stroke is vital for developing targeted therapies.