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Related Concept Videos

Vitamins01:30

Vitamins

843
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
843
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

844
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
844
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

1.0K
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
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Other Disorders of Digestive System01:30

Other Disorders of Digestive System

903
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
903
Prevalence and Incidence01:08

Prevalence and Incidence

663
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
663
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Diagnostic yield and accuracy in a tertiary referral syncope unit validating the ESC guideline on syncope: a prospective cohort study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiologyยท2020
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Related Experiment Video

Updated: Aug 5, 2025

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
11:56

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells

Published on: April 11, 2014

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[Scurvy still occurs].

Minou R Snijders Blok1,2, Marieke S S Yo1, Marjolein E M Rentinck1

  • 1Tergooi MC, afd. Interne Geneeskunde, Hilversum.

Nederlands Tijdschrift Voor Geneeskunde
|March 29, 2023
PubMed
Summary

Scurvy, a vitamin C deficiency, is surprisingly common in vulnerable groups. Early diagnosis and ascorbic acid supplementation offer a low-cost, effective treatment for its varied symptoms.

Area of Science:

  • Nutritional Science
  • Internal Medicine
  • Public Health

Context:

  • Scurvy is historically viewed as a disease of the past.
  • Vitamin C deficiency is prevalent in specific populations, including alcoholics, the elderly, and those with mental disorders or restricted diets, affecting 7.1-25% of these groups.
  • Patients present with a diverse range of symptoms beyond classical scurvy signs.

Purpose:

  • To highlight the underrecognized prevalence of vitamin C deficiency.
  • To present recent cases illustrating varied symptoms of scurvy.
  • To emphasize the efficacy of ascorbic acid supplementation.

Summary:

  • Three recent cases of vitamin C deficiency presented with bleeding, lethargy, and edema.
  • Prompt supplementation with ascorbic acid led to significant symptom improvement in all cases.

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Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
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Last Updated: Aug 5, 2025

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  • The study underscores the importance of maintaining a high index of suspicion for scurvy.

    • Impact:

    • Recognizing vitamin C deficiency in at-risk populations is crucial.
    • Ascorbic acid supplementation is a cost-effective and highly effective intervention for scurvy.
    • This approach can significantly improve patient outcomes and reduce healthcare burden.